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Editorials |

Empiric Antibiotic Use and Resistant Microbes : A “Catch-22” for the 21st Century

Constantine A. Manthous, MD, FCCP; Yaw Amoateng-Adjepong, MD, PhD
Author and Funding Information

Affiliations: Bridgeport, CT 
 ,  Dr. Manthous is Assistant Clinical Professor of Medicine, and Dr. Yaw Amoateng-Adjepong is Instructor of Medicine, Division of Pulmonary and Critical Care, Bridgeport Hospital and Yale University School of Medicine.

Correspondence to: Constantine A. Manthous, MD, FCCP, Bridgeport Hospital, 267 Grant St, PO Box 5000, Bridgeport, CT 06610; e-mail: pcmant@bpthosp.org



Chest. 2000;118(1):9-11. doi:10.1378/chest.118.1.9
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Over the past decade, clinicians have witnessed an unprecedented increase in the emergence and spread of antibiotic-resistant bacteria.13 These include methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococcus (VRE), multiple drug-resistant Gram-negative rods, and resistant Streptococcus pneumoniae. ICUs are the leading incubators of many of these resistant organisms.,16

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    Print ISSN: 0012-3692
    Online ISSN: 1931-3543