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Exhaled Nitric Oxide and Induced Sputum Analysis as Markers of Airway Inflammation in Subjects With COPD*

Philip E. Silkoff, MD; D. Martin; Juno Pak, BS; Richard J. Martin, MD, FCCP
Author and Funding Information

*From the National Jewish Medical and Research Center, University of Colorado Health Sciences Center, Denver, CO.

Correspondence to: Philip E. Silkoff, MD, National Jewish Medical and Research Center, University of Colorado Health Sciences Center, 1400 Jackson St, Denver, CO 80206



Chest. 2000;117(5_suppl_1):281S. doi:10.1378/chest.117.5_suppl_1.281S
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Abbreviations: Feno = exhaled nitric oxide; IL = interleukin; IS = induced sputum; LTB4 = leukotriene B4

Background: Airway inflammation is an important mechanism underlying deterioration in COPD and can be noninvasively assessed by exhaled nitric oxide (Feno) and induced sputum (IS). We wished to examine the short-term reproducibility of Feno and IS in a cohort of subjects with COPD.

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