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Clinical Relevance Summary*: Collagen vs Elastin in Pathogenesis of Emphysema; Cellular Origin of Elastases; Bronchiolitis vs Emphysema as a Cause of Airflow Obstruction

Gordon L. Snider, MD, FCCP
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*From the Boston Veterans Affairs Medical Center, Boston, MA.

Correspondence to: Gordon Snider, MD, FCCP, Chief Medical Service 111, Boston VA Medical Center, 150 S. Huntington Ave., Boston, MA 02130



Chest. 2000;117(5_suppl_1):244S-246S. doi:10.1378/chest.117.5_suppl_1.244S
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Extract

Abbreviation: CdCl2 = cadmium chloride

In this summary of the clinical significance of the first day’s presentations, I shall focus on three topics. The relative roles of collagen and elastin injury in the pathogenesis of emphysema, the cellular origin of elastases that may play a role in degrading elastin in emphysema, and the relative roles of bronchiolitis vs emphysema in causing airflow obstruction.

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