Tuberculosis (TB) has been and continues to be one of the most
significant pathogens in terms of human morbidity and mortality.
Although the resurgence of TB has been held in check in most developed
countries, the epidemic rages on in most developing countries of the
world. The specter of drug resistance is becoming a more credible
challenge in many parts of the world, dimming the prospects of eventual
elimination. However, great opportunities are arising as well, with an
unprecedented focus on the global aspects of TB control. This article
will review the status of TB today and put into perspective the
prospects for its elimination in the coming century.