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Editorials |

Can We Make Sense Out of Cytokines?

Alan M. Fein, MD, FCCP; Edward M. Abraham, MD
Author and Funding Information

Affiliations: Manhassett, NY 
 ,  Denver, CO 
 ,  Dr. Fein is Professor of Medicine and Director, Center for Pulmonary and Critical Care Medicine, North Shore University Hospital; Dr. Abraham is from the Division of Pulmonary Science, University of Colorado Health Sciences Center.

Correspondence to: Alan M. Fein, MD, FCCP, Professor of Medicine, Director, Center for Pulmonary and Critical Care Medicine, North Shore University Hospital, 300 Community Dr, 4th Floor, Levitt Building, Manhasset, NY 11030; e-mail: amf49@aol.com



Chest. 2000;117(4):932-934. doi:10.1378/chest.117.4.932
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Even the most experienced clinicians and scientists become uneasy when asked to explain cytokines, since these molecules have such wide-ranging biological effects. A recent MEDLINE search revealed> 193,816 citations referable to cytokines in the last decade, and > 1,700 in the last month alone. While it would be useful to put this immense body of information into a context to make it more usable for physicians in the care of their patients, this is not an easy task.

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