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Endobronchial Metastasis From Osteosarcoma of Bone*: Treatment With Intraluminal Radiotherapy

Nesrin Mogulkoc, MD; Erdem Goker, MD; Alev Atasever, MD; Ali Veral, MD; Serdar Ozkok, MD; Paul W. Bishop, BA, MB BCh
Author and Funding Information

Affiliations: *From Ege University Hospital (Drs. Mogulkoc, Goker, Veral, Ozkok, and Atasever) Izmir, Turkey; and South Manchester University Hospitals NHS Trust (Dr. Bishop), Manchester, UK. ,  Currently at North West Lung Research Centre, Wythenshawe Hospital, Manchester, UK.

Correspondence to: Nesrin Mogulkoc, MD, North West Lung Research Centre, Wythenshawe Hospital, Southmoor Rd, Wythenshawe, Manchester, M23 9LT, UK; e-mail: 100046.1102@compuserve.com



Chest. 1999;116(6):1811-1814. doi:10.1378/chest.116.6.1811
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Lung parenchymal metastases are common manifestations in patients with osteosarcoma; however, spread to the major airway itself is extremely rare. We present a young man who had been previously treated with surgical resection following preoperative chemotherapy and immediate postsurgical adjuvant chemotherapy for proximal tibial osteosarcoma. He developed metastasis to the major airways. The patient was treated with intraluminal radiotherapy (ILT) for the endobronchial metastasis. This is the first report of an endobronchial osteosarcoma that was treated with ILT with a complete endoscopic response. ILT provided excellent palliation in this particular case.

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