Pulmonary embolism in the majority of cases implies an embolus
from thrombotic material, whether it is from a vein, the right heart
chambers, the tip of an in-dwelling venous catheter, and so on.
Nevertheless, right-sided cardiac malignancies may be the source of
emboli from thrombotic or neoplastic material, and this, despite its
rarity, is a well-known complication of atrial myxomas.1–2
The absence of risk factors or evidence for thrombosis may arouse
suspicion of nonthrombotic pulmonary embolism, and in such cases
further echocardiographic evaluation of the right heart chambers may be
crucial. Among 50 cases of primary cardiac lymphoma3that
have been reported in the literature, there is only one report of
pulmonary tumor embolism, and that was from small cell
lymphoma.4 As far as we know, this is the first case of
pulmonary embolism due to large cell B-cell primary cardiac lymphoma.