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Editorials |

Prevention of Ventilator-Associated Pneumonia : Does One Size Fit All?

Richard G. Wunderink, MD, FCCP
Author and Funding Information

Affiliations: Memphis, TN 
 ,  Dr. Wunderink is Associate Director of Clinical Research, Methodist Healthcare Foundation, and Clinical Associate Professor, University of Tennessee, Memphis.

Correspondence to: Richard G. Wunderink, MD, FCCP, Methodist Healthcare Foundation, 1265 Union Ave, 501 Crews Wing, Memphis, TN 38104; e-mail: wunderir@methodisthealth.org



Chest. 1999;116(5):1155-1156. doi:10.1378/chest.116.5.1155
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Extract

Ventilator-associated pneumonia (VAP) continues to be a vexing problem in critically ill patients. Estimates of attributable mortality are variable,12 but increased duration of ventilation is a consistent finding, along with the corresponding increase in hospital days and cost. A major component of the problem is the ineffectiveness of therapy once VAP is diagnosed. Brun-Buisson et al3 have demonstrated failure rates of 49 to 62% despite the use of standard antibiotic combinations. Given the burden of VAP, both physical and financial, and the difficulties in treatment, prevention strategies would appear to be of paramount importance.


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    Print ISSN: 0012-3692
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