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Editorials |

Mechanical Ventilation in Hematopoietic Stem Cell Transplant Patients : Is There Need for Reevaluation?

Dane J. Nichols, MD; Richard T. Maziarz, MD; Marilyn T. Haupt, MD, FCCP
Author and Funding Information

Affiliations: Portland, OR 
 ,  Dr. Nichols is Assistant Professor of Medicine, Dr. Maziarz is Associate Professor of Medicine, Microbiology and Immunology, and Dr. Haupt is Professor, Department of Medicine at Oregon Health Sciences University.

Correspondence to: Dane Nichols, MD, Division of Pulmonary and Critical Care Medicine, Oregon Health Sciences University, UHS8Q, 3181 SW Sam Jackson Park Rd, Portland, OR 97221



Chest. 1999;116(4):857-859. doi:10.1378/chest.116.4.857
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Extract

Respiratory failure in the context of bone marrow transplant (BMT) is distressingly common and is associated with low long-term survival rates among patients requiring mechanical ventilation. Although disparate processes may lead to invasive ventilatory support, when multiorgan system dysfunction supervenes survival may be impossible. The bleak experience in this population has lead some authors to suggest early withdrawal of support in the presence of key organ dysfunction or, in the extreme view, withholding the option of mechanical ventilation altogether.12


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