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Cardiology Practice Today |

Incidence of Heart Failure in 2,737 Older Persons With and Without Diabetes Mellitus*

Wilbert S. Aronow, MD, FCCP; Chul Ahn, PhD
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*From the Hebrew Hospital Home (Dr. Aronow), Bronx, NY; the Department of Geriatrics and Adult Development (Dr. Aronow), Mount Sinai School of Medicine, New York, NY; and the Division of Clinical Epidemiology (Dr. Ahn), University of Texas Medical School at Houston, Houston, TX.



Chest. 1999;115(3):867-868. doi:10.1378/chest.115.3.867
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Study objectives: To investigate in older persons whether diabetes mellitus is an independent risk factor for congestive heart failure (CHF).

Design: A prospective study was performed in 2,737 older persons investigating the incidence of new CHF in persons with and without diabetes mellitus.

Setting: A long-term health-care facility.

Patients: Eight hundred sixty-five men and 1,872 women, with a mean age of 81 ± 9 years.

Measurements and results: At 43-month follow-up, new CHF developed in 272 of 690 persons (39%) with diabetes mellitus and in 467 of 2,047 persons (23%) without diabetes mellitus (p < 0.0001). Cox regression analysis showed that age (p = 0.0001, risk ratio = 1.048), hypertension (p = 0.0001, risk ratio = 2.524), coronary artery disease (p = 0.0001, risk ratio = 4.008), male gender (p = 0.0001, risk ratio = 1.399), and diabetes mellitus (p = 0.0003, risk ratio = 1.337) were significantly positively associated with the time to the development of CHF.

Conclusions: Older persons with diabetes mellitus had a 1.3 times higher chance of developing CHF than those without diabetes mellitus after controlling the confounding effects of other prognostic variables.

Abbreviations: CAD = coronary artery disease; CHF = congestive heart failure


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