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Communications to the Editor |

Squamous Cell Carcinoma With Unknown Origin : Metastasis to Mediastinal Lymph Nodes FREE TO VIEW

Ken-ichiro Inoue, MD
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First Department of Internal Medicine Matsushita Memorial Hospital Osaka, Japan



Chest. 1999;115(3):908. doi:10.1378/chest.115.3.908
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To the Editor:

The case report by Blanco and colleagues in CHEST (September 1998)1was of great interest to me. In the issue, the authors claimed the first English-language report describing metastasis of a squamous cell carcinoma of unknown origin to mediastinal lymph nodes. However, Holmes and Fouts,2 in 1970, analyzed 686 patients with a diagnosis of metastatic cancer of unknown primary origins. As their Table 2 demonstrates,2 one patient was diagnosed histologically with squamous cell carcinoma, and the principle sites of metastases were the mediastinal lymph nodes.

Correspondence to: Ken-ichiro Inoue, First Department of Internal Medicine, 5-55 Sotojima-cho, Moriguchi-city, Osaka 570-0096 Japan; e-mail: Keni@mhio.mei.co.jp

Blanco, N, Kirgan, DM, Little, AG (1998) Metastatic squamous cell carcinoma of the mediastinum with unknown primary tumor.Chest114,938-940. [PubMed] [CrossRef]
 
Holmes, FF, Fouts, TL Metastatic cancer of unknown primary site.Cancer1970;26,816-820. [PubMed]
 

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Tables

References

Blanco, N, Kirgan, DM, Little, AG (1998) Metastatic squamous cell carcinoma of the mediastinum with unknown primary tumor.Chest114,938-940. [PubMed] [CrossRef]
 
Holmes, FF, Fouts, TL Metastatic cancer of unknown primary site.Cancer1970;26,816-820. [PubMed]
 
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