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Clinical Investigations: CARDIOLOGY |

Circadian Variation of Paroxysmal Supraventricular Tachycardia*

Shih-Huang Lee, MD; Pan-Chen Chang, MD; Huei-Fong Hung, MD; Peiliang Kuan, MD; Jun-Jack Cheng, MD; Chi-Ren Hung, MD
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*From the Division of Cardiology, Department of Medicine (Drs. Lee, H.-F. Hung, Kuan, Cheng, and C.-R. Hung), Shin-Kong Wu Ho-Su Memorial Hospital, Taipei; and the Mennonite Christian Hospital (Dr. Chang), Hualien, Taiwan.



Chest. 1999;115(3):674-678. doi:10.1378/chest.115.3.674
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Background: Various clinical manifestations of cardiovascular diseases have a pattern of circadian variation. In this study, we investigated whether the onset and duration of paroxysmal supraventricular tachycardia (PSVT) has a circadian variation.

Methods and results: In our analysis, we included 105 patients with 498 PSVT episodes. In this study, the onset of PSVT did not have a uniform distribution throughout the 24-h period. There were nearly equal peaks in the time periods from 8:00 to 9:00 am, 12:00 to 1:00 pm, and 5:00 to 6:00 pm, with a trough at night. The duration of PSVT also did not show a uniform distribution throughout the 24-h period; it increased significantly during the daytime, with a peak between 1:00 and 2:00 pm, another peak between 6:00 and 7:00 pm, and a significant reduction at night.

Conclusions: The onset and duration of PSVT showed a circadian variation. However, the time-oriented antiarrhythmic therapy for preventing PSVT needs further study.

Abbreviations: PSVT = paroxysmal supraventricular tachycardia

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