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Editorials |

Cryptococcal Lung Disease in Patients Without HIV Infection

George A. Sarosi, MD, FCCP
Author and Funding Information

Affiliations: Indianapolis, IN 
 ,  Professor of Medicine, Indiana University School of Medicine, and Chief, Medical Service, Roudebush VA Medical Center.

Correspondence to: George A. Sarosi, MD, FCCP, Chief, Medical Service, Roudebush VA Medical Center, 1481 W. 10th Street, Indianapolis, IN 46202-2803; e-mail: sarosi_m+d+george_a@indianapolis.va.gov



Chest. 1999;115(3):610-611. doi:10.1378/chest.115.3.610
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Cryptococcus neoformans var neoformans is a truly cosmopolitan fungus, recognized to cause human disease on all five continents. Its ecologic niche is poorly defined, but it has been associated with pigeon and other bird droppings. Interestingly, the birds themselves have nothing to do with the fungus, since the bird’s elevated body temperature of 41.5° to 43.3°C is too high to promote fungal growth. The role of bird excreta is mainly to provide the fungus with a ready supply of organic nitrogen.


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  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543