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Thoracic Involvement With Pheochromocytoma*: A Review

Sunder Sandur, MD; Asok Dasgupta, MD; Joel L. Shapiro, MD; Alejandro C. Arroliga, MD, FCCP; Atul C. Mehta, MD, FCCP
Author and Funding Information

*From the Department of Pulmonary and Critical Care Medicine (Drs. Sandur, Dasgupta, Arroliga, and Mehta) and the Department of Pathology (Dr. Shapiro), The Cleveland Clinic Foundation, Cleveland, OH.



Chest. 1999;115(2):511-521. doi:10.1378/chest.115.2.511
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Pulmonary manifestations of pheochromocytoma are infrequent and are not well documented. A MEDLINE search in the English language revealed no cases of endobronchial involvement from a pheochromocytoma. We report a case of endobronchial metastases in a 37-year-old woman known to have a recurrent extra-adrenal pheochromocytoma. She presented with symptoms of wheezing and a nonproductive cough for 8 months and was being treated for asthma. A flexible bronchoscopy with endobronchial biopsy established the diagnosis. The patient underwent a Nd-YAG laser photoresection (LPR) to ablate the tumor, which was followed by placement of a Wallstent (Pfizer Medical Technology Group; Rutherford, NJ). She remains well 18 months later, having required multiple palliative LPRs. To our knowledge, this is the first reported case of endobronchial pheochromocytoma. The pulmonary manifestations of this rare disease and their management are reviewed.

Abbreviations: BI = bronchus intermedius; FB = flexible bronchoscopy; LPR = laser photoresection; MIBG-I131 = metiodobenzyl-guanidine-iodine 131; RML = right middle lobe; SCLC = small cell lung carcinoma

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