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Multiple Nodular Opacities on Chest Radiograph After Lung Transplantation*

Jan W. K. van den Berg, MD; Eric J. van der Jagt, MD, PhD; Gerard H. Koëter, MD, PhD; Wim Van der Bij, MD, PhD
Author and Funding Information

*From the Departments of Pulmonary Diseases and Radiology, University Hospital Groningen, Groningen, the Netherlands.



Chest. 1999;115(1):272-274. doi:10.1378/chest.115.1.272
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Extract

At the outpatient clinic, a 47-year-old woman was seen for routine follow-up after lung transplantation. The patient had received a right-sided lung transplant for primary pulmonary hypertension 2 years earlier. Her follow-up stated eight episodes of acute rejection, treated with high doses of corticosteroids. After the eighth episode, just over 6 months after transplantation, an open lung biopsy was performed, revealing obliterative bronchiolitis. It was then decided to replace azathioprine by mycophenolate mofetil, whereas treatment with cyclosporine and corticosteroids was continued. Apart from the rejection episodes, Aspergillus fumigatus was isolated from the respiratory tract on several occasions.

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