Articles |

Treatment Success With a Mandibular Advancement Device Is Related to Supine-Dependent Sleep Apnea FREE TO VIEW

Marie Marklund; Maurits Persson; Karl A. Franklin
Author and Funding Information

Affiliations: From the Department of Orthodontics, Umeå University, University Hospital, Umeå, Sweden,  From the Department of Respiratory Medicine, University Hospital, Umeå, Sweden

Marie Marklund, DDS, Department of Orthodontics, Umeå University, SE-901 87 Umeå, Sweden

1998 by the American College of Chest Physicians

Chest. 1998;114(6):1630-1635. doi:10.1378/chest.114.6.1630
Text Size: A A A
Published online


Study objective: To evaluate the effect of a mandibular advancement device in patients with supine-dependent sleep apnea and patients with non-supine-dependent sleep apnea.

Design: Prospective study.

Setting: Department of Respiratory Medicine, University Hospital, Umeå, Sweden.

Patients: Twenty-six patients with obstructive sleep apnea.

Intervention: Individually fabricated and adjusted mandibular advancement devices.

Measurements: Overnight polysomnographic sleep recordings with and without the device. Supine-dependent sleep apnea was defined when the supine apnea-hypopnea index was ≥10, together with a lateral apnea-hypopnea index of < 10. Non-supine-dependent sleep apnea was considered when the lateral apnea-hypopnea index was ≥ 10.

Results: In 12 patients with supine-dependent sleep apnea, the device reduced the supine apnea-hypopnea index from a median of 41 (range, 16 to 70) to 5.9 (range, 0.0 to 15) (p < 0.01). In 14 patients with non-supine-dependent sleep apnea, the treatment reduced the supine apnea-hypopnea index from 44 (range, 1.8 to 73) to 21 (range, 6.3 to 60) (p < 0.05) and the lateral apnea-hypopnea index from 21 (range, 12 to 70) to 4.5 (range, 0.0 to 31) (p < 0.01). The odds ratio for a successful apnea reduction to an apnea-hypopnea index of < 10 in both the supine and the lateral positions was 30 for supine-dependent sleep apnea adjusted for age, obesity, mandibular advancement, and mandibular opening (p < 0.01).

Conclusion: Successful apnea reduction with a mandibular advancement device is highly related to supine-dependent sleep apnea.




Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Find Similar Articles
CHEST Journal Articles
PubMed Articles
Mandibular Advancement Appliance for Obstructive Sleep Apnea Treatment. Adv Exp Med Biol Published online Sep 20, 2016;
Oral Appliances in Obstructive Sleep Apnea. Otolaryngol Clin North Am Published online Oct 6, 2016;
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543