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Large Airway Disease Associated With Inflammatory Bowel Disease

Avrum Spira; Ronald Grossman; Meyer Balter
Author and Funding Information

Affiliations: From the Department of Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada,  From the University of Toronto, and the Division of Respirology, Mount Sinai Hospital, Toronto, Ontario, Canada

Affiliations: From the Department of Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada,  From the University of Toronto, and the Division of Respirology, Mount Sinai Hospital, Toronto, Ontario, Canada


1998 by the American College of Chest Physicians


Chest. 1998;113(6):1723-1726. doi:10.1378/chest.113.6.1723
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Abstract

Lung disease is a rare complication of inflammatory bowel disease (IBD). Herein is a series of seven IBD patients who developed new, persistent and unexplained symptoms of respiratory disease, particularly chronic productive cough. Using a CT scan of the chest, a diagnosis of bronchiectasis was made in five patients, while the diagnosis of chronic bronchitis was made in two patients. Factors, other than IBD, that could account for pulmonary disease in these patients were absent. Several important clinical patterns for IBD-associated large airway disease were uncovered and are reviewed in light of earlier case reports in the medical literature. A discussion regarding the possible pathogenesis of IBD-associated airway disease follows.


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