0
Articles |

Pneumococcal Bacteremia in Childhood : A 6-Year Experience in a Community Hospital

Balagangadhar R. Totapally; William T. Walsh
Author and Funding Information

From the Departments of Pediatrics and Pathology, Hurley Medical Center, Flint, Mich.


1998 by the American College of Chest Physicians


Chest. 1998;113(5):1207-1214. doi:10.1378/chest.113.5.1207
Text Size: A A A
Published online

Abstract

Objective: To review the clinical and laboratory findings in children with pneumococcal bacteremia during a 6-year period between 1989 and 1995.

Design: Retrospective review of medical records identified from computer-generated blood culture records.

Setting: Hurley Medical Center in Flint, Mich, a community teaching hospital affiliated with Michigan State University.

Measurements: Data concerning age, gender, race, clinical findings, laboratory features, nature of antibiotic therapy, source of bacteremia, and outcome were obtained from patient medical records.

Results: Most (68%) of the children with pneumococcal bacteremia were <2 years of age. About 50% of the cases of invasive pneumococcal disease in childhood occurred between February and May. Focal source of bacteremia was as follows: 11.5% had meningitis, 37% had pneumonia, 30% had otitis media, and 33% had no focal source. Overall, 60% of children were African-Americans, although in children with meningitis, whites were predominant (p<0.04). Leukocytosis was present in 81% and bandemia >1,500/µL was present in 53% of children. The overall mortality was 1.6% with a case fatality rate for meningitis of 14%. Penicillin resistance was found in 6.5% of pneumococcal isolates, although during 1 study year (1993), 17% of all pneumococcal isolates from all sources in the same hospital were found to be penicillin resistant.

Conclusions: Clinical and laboratory findings seen in children with pneumococcal bacteremia at a community hospital are presented with a review of literature. Pneumococci isolated from sterile body sites were found to be less resistant to antibiotics compared with those isolated from nonsterile body sites.


Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Find Similar Articles
CHEST Journal Articles
PubMed Articles
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543