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Considerations in Optimizing Radiation Therapy for Non-small Cell Lung Cancer FREE TO VIEW

Joel S. Greenberger; Sanjeev Bahri; James Jett; Chandra Belani; Andre Kalend; Michael Epperly
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From the Department of Radiation Oncology, University of Pittsburgh Medical Center and University of Pittsburgh Cancer Institute

1998 by the American College of Chest Physicians

Chest. 1998;113(1_Supplement):46S-52S. doi:10.1378/chest.113.1_Supplement.46S
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Irradiation therapy for lung cancer is mostly restricted to conventional methods. To improve therapeutic ratio, we have combined a treatment planning and a gene therapy approach. Three-dimensional conformal radiotherapy is described as carried out by methods of gene therapy for radiation protection using the manganese-superoxide-dismutase transgene delivered by inhalation gene transfer. These methods may improve therapeutic outcomes in lung cancer.




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