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Successful Treatment of Sclerosing Cervicitis and Fibrosing Mediastinitis With Tamoxifen

Brent A. Savelli; Marianne Parshley; Melvin L. Morganroth
Author and Funding Information

Affiliations: From the Providence Medical Center, Department of Medical Education, Department of Internal Medicine, Oregon Health Sciences University, Portland,  From the Pulmonary and Critical Care Division, Department of Internal Medicine, Oregon Health Sciences University, Portland

Affiliations: From the Providence Medical Center, Department of Medical Education, Department of Internal Medicine, Oregon Health Sciences University, Portland,  From the Pulmonary and Critical Care Division, Department of Internal Medicine, Oregon Health Sciences University, Portland


1997 by the American College of Chest Physicians


Chest. 1997;111(4):1137-1140. doi:10.1378/chest.111.4.1137
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Abstract

Fibrosing mediastinitis and sclerosing cervicitis are fibrosclerotic disorders akin to retroperitoneal fibrosis, with presenting symptoms related to local pain or viscus obstruction or both. No definitive treatment is known. This is the first report of these disorders dramatically responding to tamoxifen citrate and prednisone.


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