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Mesothelioma and Radical Multimodality Therapy: Who Benefits?

David J. Sugarbaker; Michael T. Jaklitsch; Michael J. Liptay
Author and Funding Information

From the Division of Thoracic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston


1995 by the American College of Chest Physicians


Chest. 1995;107(6_Supplement):345S-350S. doi:10.1378/chest.107.6_Supplement.345S
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Published online

Abstract

The incidence of malignant pleural mesothelioma is increasing. Untreated, patients with this disease experience a rapid and horrendous clinical decline. Surgery plays a role in the diagnosis, staging, and treatment of this malignancy. Surgery, chemotherapy, and radiotherapy alone have been unable to achieve major improvements in survival for most patients. More recent phase II trials suggest that surgery, at one time a purely palliative approach, may have a potentially curative role when used in combination with chemotherapy and radiotherapy.


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