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Acute hypoxemic respiratory failure following intrapleural thrombolytic therapy for hemothorax.

M D Frye; M Jarratt; S A Sahn
Chest. 1994;105(5):1595-1596. doi:10.1378/chest.105.5.1595
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Abstract

Intrapleural instillation of thrombolytic agents has been useful in the treatment of hemothorax when thoracostomy tube drainage is unsuccessful. We present a patient who developed acute hypoxemic respiratory failure following the intrapleural instillation of both streptokinase and urokinase 24 h apart. Hypoxemia most likely resulted from a direct effect of the products of fibrinolysis on the pulmonary circulation.


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