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The Role of Neuropeptides in Asthma FREE TO VIEW

Joan D. Boomsma; Sami I. Said
Author and Funding Information

The Pulmonary Division, Department of Internal Medicine, Northwestern University Medical School, and the University of Illinois College of Medicine at Chicago and Veterans Affairs West Side Medical Center, Chicago.


1992, by the American College of Chest Physicians.


Chest. 1992;101(6_Supplement):389S-392S. doi:10.1378/chest.101.6_Supplement.389S
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Abstract

In the last several years, there has been a tremendous increase in our understanding of the neural control of the airways and the effects of peptides on the lung. The identification of a large number of neuropeptides with potent biologic activity and the characterization of nonadrenergic noncholinergic nerve pathways with peptide neurotransmitters have expanded our concepts of airway control. Additionally, this new information has led to speculation about the pathogenesis of asthma and the potential for novel therapies. We still know very little about the precise role of these neuropeptides in the normal lung or disease states, but each advance in knowledge brings us closer to the ultimate goal of providing new approaches to the treatment of asthma.


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