PURPOSE: The purpose of this study is to evaluate the usefulness of airway resistance via impulse oscillometry (IOS) in patients with chronic neonatal lung disease, CNLD. IOS at 5 Hz measures total respiratory system resistance. IOS at 20Hz measures central airway resistance.
METHODS: We retrospectively reviewed the charts of 24 pediatric patients with CNLD between the ages of 5 of 14 years. We obtained their spirometry for the FEV1 percent predicted value and the percent predicted value of airway resistance via impulse oscillometry at 5Hz and 20Hz.
RESULTS: The mean IOS at 5Hz was 122.75% and at 20Hz was 63.42% The mean FEV1 was 68.81%. There was a inverse correlation of -0.48421 between the FEV1 percent predicted and airway resistance at 5Hz. There was no correlation of FEV1 with airway resistance at 20Hz.
CONCLUSIONS: The airway resistance at 5Hz and FEV1 were inversely related. There was no additional information from obtaining airway resistance at 20Hz.
CLINICAL IMPLICATIONS: Due to CNLD, pediatric patients may have higher central airway resistance that may not be accounted for by the FEV1.
DISCLOSURE: The following authors have nothing to disclose: Sneha Taylor, Stamatia Alexiou, Glenn Hildreth, Kevin Maupin
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