PURPOSE: A relatively rare complication of Wegener's granulomatosis is involvement of the subglottis and upper part of the trachea. Many patients are treated as if they have asthma.
METHODS: We present a very rare case of subglottic stenosis as a complication of Wegener's granulomatosis.
RESULTS: A 48 yrs old woman was admitted to the hospital for dispnea and stridor. She has been receiving ashma and allergic rhinitis medications for 3 years. Her symptoms have got worsened throughout last 6 months. Her medical history revealed polen allergy. She was suffering dyspnea especially on excertion. On physical examination, rhonchi were heard on auscultation both inspiratory and expiratory along with stridor. Routine lab test were in normal limits. CT of thorax showed the spindle shaped trachea beneath the glottis. Spirometry revealed a restriction with FVC: 65% and FEV1: 64%. Fiberoptic bronchoscopy clarified that there is a ring shaped stenosis in the subglottic portion of trachea. The stenosis was dilated with mechanical dilatation and mucosal biopsies were performed. The p-ANCA was found to be positive. The patient was diagnosed as Wegener's granulomatosis with a complication of tracheal stenosis.
CONCLUSIONS: Wegener's granulomatosis should be kept in mind in evaluation of stridor and subglottic stenosis although it is a very rare condition.
CLINICAL IMPLICATIONS: The differential diagnosis of stridor.
DISCLOSURE: The following authors have nothing to disclose: Ali Fidan, Nesrin Kiral, Sevda Comert, Serap Diktas, Banu Salepci, Benan Caglayan
No Product/Research Disclosure Information