Poster Presentations: Wednesday, October 26, 2011 |

Assessment of Periodic Limb Movements in Right-handed Versus Left-handed Patients FREE TO VIEW

Mohd Kanjwal, MD; Dawn-Alita Hernandez, MD
Chest. 2011;140(4_MeetingAbstracts):816A. doi:10.1378/chest.1119044
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PURPOSE: Periodic limb movement disorder is characterized by rhythmic movements of lower extremity and results in complaints of insomnia and excessive day time sleepiness.Our main objective was to compare periodic limb movements in right handed patients versus those in left handed patients. we would like to investigate hemispheric dominance Vs limb involment in periodic leg movement disorder to direct us to further investigations focusing on spinal reflex arcs versus cortical/upper motor neuronal processes.

METHODS: This was a retrospective analysis of 100 patients of periodic limb movement disorder. These patients were categorized into left handed and right handed patients. These two groups of patients (Left vs. Right handed) were compared for various clinical and polysomnography characteristics. Continuous data is presented as mean± SD and categorical as percentages.

RESULTS: Eighty four patients were right handed and 16 left handed. Sixty nine percent of right handed patients had bilateral limb movements compared to 94 % of left handed patients(p= 0.04). Age, sex, race and predominant left sided movement was not significantly different in the two groups.

CONCLUSIONS: Left handed people have significantly higher chances of having bilateral limb movements compared to right handed people.

CLINICAL IMPLICATIONS: To date , no one has investigates if handedness ( left or right) affects the side(s) involved in periodic leg movement disorder, it would be of value to know whether right or left hemisphere motor dominanace affects PLMD because this would lead studies to focus on cortical irritants stimulating the movement disorder.

DISCLOSURE: The following authors have nothing to disclose: Mohd Kanjwal, Dawn-Alita Hernandez

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