PURPOSE: Chronic medical conditions are commonly associated with sleep disorders. Chronic respiratory diseases such as Chronic Obstructive Pulmonary Disease (COPD), particularly moderate or severe disease, have been linked to a higher prevalence of sleep disorders such as insomnia, restless leg syndrome (RLS) and Obstructive Sleep Apnea-Hypopnea Syndromes (OSAHS). We aim to investigate prevalence of sleep disorders and its determinants in patients with chronic respiratory disease.
METHODS: We studied a cohort of veterans who underwent pulmonary function testing at VA Medical Center in Houston between 2000 and 2008. A compilation of questionnaires, including St.George’s Respiratory Questionnaire (SGRQ), Pittsburgh Sleep Quality Index (PSQI), and SF12, was mailed to measure the effect of respiratory disease on their daily lives including functional limitation, sleep quality, and quality of life, respectively. Responses were analyzed and correlated with their pulmonary function values.
RESULTS: A total number of 1929 surveys were mailed, of which, 363 responded (19%) with mean age 69 (10), 97% male, and mean FEV1 68% (23%). The subjective mean sleep latency was 32.9 min (31.9), with 83.5% reporting poor sleep quality (score of > 5 in PSQI) and mean total SGRQ 56.8 (22.9) and mean SF12 Physical of 30.4 (11.8) and Mental of 44.9 (12.8). The sleep latency did not correlate with presence of obstruction but correlated with presence of respiratory symptoms.
CONCLUSIONS: Prevalence of sleep disorders is high in our cohort of patients with chronic respiratory conditions. Our results indicate that higher prevalence of sleep disorders correlates with degree of morbidity due to respiratory disease rather than the presence of obstructive airway disease or degree of abnormality on pulmonary function tests.
CLINICAL IMPLICATIONS: Patients with chronic respiratory disease should be screened for presence of sleep disorders because poor sleep quality may further impact their quality of life.
DISCLOSURE: The following authors have nothing to disclose: Vishal Sawhney, Joseph Rosen, Bridget Baringer, Hashir Majid, Max Hirshkowitz, Amir Sharafkhaneh
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