Poster Presentations: Wednesday, October 26, 2011 |

The Role of Laryngopharyngeal Reflux in Chronic Obstructive Pulmonary Disease: The Preliminary Results of TROYACHEST-001 Study FREE TO VIEW

Arzu Mirici, MD; Oguz Guclu, MD; Ugur Gonlugur, MD; Muammer Yildiz, MD; Ozan Barutcu, MD; Sefa Derekoy, MD
Chest. 2011;140(4_MeetingAbstracts):571A. doi:10.1378/chest.1118424
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PURPOSE: Laryngopharyngeal reflux (LPR) is defined as the movement of gastric content towards the larynx and the pharynx and it may cause respiratory symptoms or difficulty in their control. We aimed to find the frequency of LPR in chronic obstructive pulmonary disease (COPD) patients and to investigate its effect on COPD symptoms.

METHODS: We prospectively analyzed pulmonary function test parameters, body-mass index, MRC dyspnea scale, Beck depression scale, and a questionnaire developed by Belafsky and colleagues before laryngoscopic examination.

RESULTS: At baseline 35 (33 male, 2 female) COPD patients completed LPR and COPD symptom questionnaires and 20 (57%) were diagnosed with LPR based on laryngeal examination. There was not a significant correlation between LPR and FEV1, or body-mass index, or smoking. In the patients with LPR, there was a positive correlation between dyspnea scale and the COPD severity (53% in stage II, 59% stage III). Laryngopharyngeal reflux observed 71% of the patients who had Beck depression inventory score more than 17.

CONCLUSIONS: Our preliminary results showed the impact of laryngopharyngeal reflux on health-related quality of life in chronic obstructive pulmonary disease.

CLINICAL IMPLICATIONS: Laryngopharyngeal reflux is a contributing factor for dyspnea in COPD.

DISCLOSURE: The following authors have nothing to disclose: Arzu Mirici, Oguz Guclu, Ugur Gonlugur, Muammer Yildiz, Ozan Barutcu, Sefa Derekoy

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