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Poster Presentations: Wednesday, October 26, 2011 |

Cardiac Bioimpedance for Noninvasive Assessment of Hemodynamics in Patients With Pulmonary Hypertension FREE TO VIEW

Ralf Kaiser, MD; Christian Lensch, MD; Robert Bals, PhD; Heinrike Wilkens, PhD
Chest. 2011;140(4_MeetingAbstracts):715A. doi:10.1378/chest.1117851
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Abstract

PURPOSE: Pulmonary hypertension (PH) is a serious disease diagnosed by echocardiography and right heart catheterization. Left ventricular dysfunction and decreased cardiac output is a common feature in pulmonary hypertension. The aim of this study was to evaluate cardiac bioimpedance (CBI) as a possible non-invasive tool in hemodynamic monitoring.

METHODS: 19 patients with IPAH or CTEPH (19-76 years) and 6 healthy volunteers were measured simultaneously by thoracic echocardiography and non-invasive cardiac bioimpedance (CBI) using a BoMed NCCOM3. Parameters were standardized by body surface area. Linear regression analysis and F-Test were performed.

RESULTS: Left ventricular end diastolic volume index in CBI correlated with echocardiography measurements in both M-Mode (r=0,6181; p=0,002) and B-Mode (Simpson, r=0,8431, p<0,001). Also the Stroke index in CBI correlated with the estimated stroke index in M-Mode (r=0,7077; p<0,001) and B-Mode (Simpson, r=0,7946; p<0,001).

CONCLUSIONS: In patients with IPAH or CTEPH, cardiac bioimpedance might be a useful non-invasive tool in monitoring left ventricular hemodynamics including left ventricular preload and cardiac output.

CLINICAL IMPLICATIONS: Cardiac bioimpedance might be useful in evaluation of hemodynamics of patients with pulmonary hypertension during outpatient management once a individual baseline is established. Furthermore it provides additional information on cardiac contractility, which need further investigation in pulmonary hypertension.

DISCLOSURE: The following authors have nothing to disclose: Ralf Kaiser, Christian Lensch, Robert Bals, Heinrike Wilkens

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