PURPOSE: to detect the impact of anxiety on shaping the prevalence of gastro-intestinal reflux disease (GERD) in patients with severs chronic obstructive pulmonary disease (COPD
METHODS: we examined the prevalence of symptomatic GERD, using the Vigneri score, in 29 male patients with COPD. Esophageal 24 h pH monitoring was used to document the diagnosis of GERD in symptomatic group. Beck Anxiety inventory was used to detect the impact of anxiety on expressing GERD symptoms.
RESULTS: reflux disease symptoms were recorded in eighteen patients of the studied group (62%). GERD was diagnosed, based on esophageal 24 h PH monitoring, in only 11 patients of those who expressing symptoms of GERD. Mean of Anxiety score was correlated significantly with the number and frequency of symptom presentation in patient with symptoms of GERD reflecting the attribution of differnt symptoms of anxiety to the GERD syndrom. Also Anxiety scores correlated positively with time (total) PH reflecting the effect of anxiety on the sverity of GERD syndrom.
CONCLUSIONS: True GERD was documented in a fewer number of them. Psychological factors, such as anxiety and somatisation may play a role, particularly in those patients without esophageal inflammation
CLINICAL IMPLICATIONS: Patients with severe chronic obstructive pulmonary disease have a high prevalence of symptomatic gastro-oesophageal reflux.
DISCLOSURE: The following authors have nothing to disclose: Sherif Alsayed
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