PURPOSE: This project compares the mortality and prevalence of small cell lung cancer (SCLC) and non small cell lung cancer (NSCLC) between Detroit and other registries from the Surveillance, Epidemiology, and End Results (SEER) database.
METHODS: The SEER database was analyzed for cases of SCLC and NSCLC from 1973-2007. The primary outcome was cancer specific survival between Detroit and other registries by ethnicity. The secondary outcome was determining the prevalence of SCLC and NSCLC in all registries. Statistical Analysis System (SAS) was used to analyze survival.
RESULTS: A total of 105,522 cases of SCLC and 3,094,764 cases of NSCLC were identified. Iowa has the highest prevalence of NSCLC and SCLC followed closely by Detroit for all races. In white SCLC patients, only Utah, and California excluding Los Angeles (LA), San Francisco (SF), and San Jose Monterey (SJM) have worse survival than Detroit. There is no significant difference in mortality in New Mexico, LA, rural Georgia, Alaska, Louisiana, and SF from Detroit. Connecticut, Hawaii, Seattle, SJM, Atlanta, Iowa, Kentucky, and New Jersey have better survival than Detroit There was no difference in mortality between Detroit and other registries in black and other nonwhite SCLC patients. In white NSCLC patients, rural Georgia, Kentucky, and Louisiana have worse survival than Detroit. San Francisco, Connecticut, Hawaii, Iowa, New Mexico, Seattle, Utah, Atlanta, SJM, LA, California excluding LA/SJM/SF, New Jersey have better survival than Detroit. In black NSCLC patients, Iowa had lower survival than Detroit. There was no difference in mortality comparing Detroit to New Mexico, Seattle, Utah, Alaska, or Kentucky. San Francisco, Connecticut, Hawaii, Atlanta, SJM, LA, rural Georgia, California excluding SF/SJM/LA, Louisiana, and New Jersey had better survival than Detroit. For other nonwhite NSCLC patients, Alaska had worse survival than Detroit. There was no difference in mortality between Detroit and SF, Hawaii, Iowa, Seattle, SJM, LA, rural Georgia, Kentucky, Louisiana, or California excluding LA/SJM/SF. Connecticut, New Mexico, Utah, Atlanta, and New Jersey had better survival than Detroit.
CONCLUSIONS: Differences in mortality exist between registries which could reflect differences in health care access and tumor presentation.
CLINICAL IMPLICATIONS: More studies should be done in order to identify these factors.
DISCLOSURE: The following authors have nothing to disclose: Ali Eskandar, Saad Sirop, Maral Kojaian, Jami Foreback, Ragnhild Bundesmann, Mohammed Kanaan, Yan Xie
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