PURPOSE: 19-51% of inferior acute myocardial infarction(AMI) patients combine with right ventricular infarction(RVI). RVI is associated with a highly increased in-hospital mortality. Therefore, early diagnosis of RVI in inferior acute myocardial infarction is very important. This study was planned to investigate the usefulness of B-type natriuretic peptide(BNP) in the early diagnosis of RVI.
METHODS: The patients who were diagnosed as inferior AMI and primary coronary intervention done within 6 hours were selected for this study. The subject patients(n=100) had a significant luminal narrowing at right coronary artery, and no specific findings in left coronary artery on coronary angiograms. The patients were divided into group A for those who had a proximal lesion and RVI, group B with a proximal lesion but without RVI, and group C with a distal lesion.
RESULTS: Twenty eight of the 100 subject patients suffered from RVI. Among 72 patients who did not accompany with RVI, 26(36%) had a significant stenosis in their proximal portion while 46(64%) had a significant distal stenosis. The level of BNP was 298.8±138.5 pg/mL in group A(n=28), 83.2±53.6 pg/mL in group B(n=26), and 68.1±46.9 pg/mL in group C(n=46) respectively. BNP was increased when RVI was accompanied regardless of the site of the lesion.
CONCLUSIONS: BNP is a useful marker for diagnosis of combined RVI in case of inferior AMI
CLINICAL IMPLICATIONS: BNP is a useful marker for diagnosis of combined RVI in case of inferior AMI.
DISCLOSURE: The following authors have nothing to disclose: Hyeon Gook Lee, Seong-Man Kim, Kyoung-Im Cho, Kiuk Kim, Byung-Jae Ahn, Tae-Ik Kim
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