PURPOSE: Patients with chronic obstructive pulmonary disease (COPD) often suffer from depression, which is one of the most common and modifiable comorbidities of COPD. We evaluated the association between depression and COPD severity assessed by two criteria: the Global initiative for chronic Obstructive Lung Disease (GOLD) stage and the body mass index, degree of airflow obstruction, dyspnea, and exercise capacity (BODE) index.
METHODS: This was a multicenter prospective cross-sectional study in 245 patients with stable COPD. Depression was assessed using the Centers for Epidemiologic Studies Depression (CES-D) scales. Data were analyzed with descriptive statistics, Spearman correlation and multiple regression.
RESULTS: The overall prevalence of depression was 17.6%. The prevalence of depression increased with increasing BODE stages (r = 0.16, p = 0.014) but no with increasing GOLD stages (r = -0.01, p = 0.898). Among the components of the BODE index MMRC was an independent predictor for depression.
CONCLUSIONS: The present study suggests that the BODE scoring system has better correlation to depression than the GOLD staging criteria in patients with COPD.
CLINICAL IMPLICATIONS: This study provides support for the use of the multidimensional scoring system as a new classification system of COPD.
DISCLOSURE: The following authors have nothing to disclose: Kiuk Kim, Mi hyun Kim, Kwangha Lee, Hye-Kyung Park, Doo Soo Jeon, Yun Seong Kim, Min Ki Lee, Hyeon Gook Lee, Soon Kew Park
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