PURPOSE: To describe the surgical patients at University Hospital of Lyon Sud for lung cancer in non-small cell between 1998 and 2002 and highlight the factors associated with mortality and survival
METHODS: All patients who underwent surgery for non-small cell lung cancer at University Hospital of Lyon Sud between 1 January 1998 and December 31, 2002 were included. The data concerning the treatment and fate of these patients were collected retrospectively. Patient characteristics and treatment were studied. An analysis of factors associated with mortality and survival was performed using a univariate and multivariate statistical approach.
RESULTS: 582 patients were included. The average age was 62 years, sex ratio was 4.6 men to 1 woman. The 30-day mortality was 2.1%, median survival was 56.8 months with survival rates at 1 year of 81% and 48% at 5 years. Factors significantly decreasing survival in multivariate analysis were sex (male), TNM stage (stage greater than I), adjuvant therapy (radiotherapy), age (over 65), and histological type (adenocarcinoma).
CONCLUSIONS: The results of our study were found valid. The analysis of factors associated with survival confirmed the known associations. This study may remind Cambodian practitioners and patient effectiveness of surgery on non-small cell lung cancer, especially when detected early. This justifies taking attention to the respiratory symptoms in risk patients (particularly in smokers).
CLINICAL IMPLICATIONS: non-small cell lung cancer, surgical treatment, risk factors of mortality, survival.
DISCLOSURE: Sophors Chan: Grant monies (from sources other than industry): laboratory
The following authors have nothing to disclose: Jose Guerra, Sebatien Couraud, Benoit Guibert, Pierre Jean Souquet
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