Poster Presentations: Tuesday, October 25, 2011 |

Effect of Medical Therapy on Cardiovascular Events in an Outpatient Cardiology Practice FREE TO VIEW

Hoang Lai, MD; Wilbert Aronow, MD; Anthony Mercando, MD; Mala Sharma, MD; Phoenix Kalen, MS; Harit Desai, MD; Kaushang Gandhi, MD; Harshad Amin, MD; Trung Lai, BS
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New York Medical College, Valhalla, NY

Chest. 2011;140(4_MeetingAbstracts):250A. doi:10.1378/chest.1099729
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PURPOSE: This study investigated the effect of medical therapy on incidences of myocardial infarction (MI), percutaneous coronary intervention (PCI), and coronary artery bypass graft surgery (CABGS) in an outpatient cardiology practice.

METHODS: Chart reviews were performed in 1675 patients (1189 men and 486 women), mean age 72 years, seen in 2008. Mean follow-up duration was 60 months during 1977 to 2008.

RESULTS: Of 1675 patients, MI occurred in 708 patients (42%), PCI in 715 patients (43%), and CABGS in 630 patients (38%). Stepwise logistic regression analysis showed significant independent risk factors for MI were statins (odds ratio = 0.07, p <0.001), beta blockers (odds ratio = 0.14, p<0.001), angiotensin-converting enzyme (ACE) inhibitors (odds ratio = 0.27, p<0.001), angiotensin receptor blockers (ARBs) (odds ratio = 0.09, p<0.001), and aspirin (odds ratio = 0.17, p<0.001). Significant independent risk factors for PCI were statins (odds ratio = 0.14, p <0.001), beta blockers (odds ratio = 0.25, p<0.001), ACE inhibitors (odds ratio = 0.25, p<0.001), and ARBs (odds ratio = 0.18, p<0.001). Significant independent risk factors for CABGS were statins (odds ratio = 0.16, p<0.001), beta blockers (odds ratio = 0.41, 95% CI, 0.30-0.55, p<0.001), ACE inhibitors (odds ratio = 0.38, p<0.001), ARBs (odds ratio = 0.19, p<0.001), and aspirin (odds ratio = 0.45, p<0.001).

CONCLUSIONS: In an outpatient cardiology practice, use of statins, beta blockers, ACE inhibitors, ARBs, and aspirin reduced incidences of MI, PCI, and CABGS.

CLINICAL IMPLICATIONS: Use of statins, beta blockers, ACE inhibitors, ARBs, and aspirin reduced the incidences of MI, PCI, and CABGS in an outpatient cardiology practice.

DISCLOSURE: The following authors have nothing to disclose: Hoang Lai, Wilbert Aronow, Anthony Mercando, Mala Sharma, Phoenix Kalen, Harit Desai, Kaushang Gandhi, Harshad Amin, Trung Lai

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