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Postgraduate Education Corner: PULMONARY AND CRITICAL CARE PEARLS |

A 48-Year-Old Woman With a Large Mediastinal Mass

Matthew Ferrantino, MD; James Eichelberger, MD; H. Richard Burack, MD, PhD; Faqian Li, MD, PhD; F. Eun-Hyung Lee, MD
Author and Funding Information

From the Divisions of Pulmonary and Critical Care Medicine (Drs Ferrantino and Lee), Cardiology (Dr Eichelberger), and Pathology (Drs Burack and Li), University of Rochester Medical Center, Rochester, NY.

Correspondence to: F. Eun-Hyung Lee, MD, Division of Pulmonary and Critical Care Medicine, University of Rochester Medical Center, 601 Elmwood Ave, Box 692, Rochester, NY 14642; e-mail: eunhyung_lee@urmc.rochester.edu


Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (http://www.chestpubs.org/site/misc/reprints.xhtml).


© 2010 American College of Chest Physicians


Chest. 2010;138(5):1260-1264. doi:10.1378/chest.10-0908
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Extract

A 48-year-old black woman presented to the ED with a 1-year history of progressive dyspnea with exertion and chest discomfort. Four years prior, she presented to the ED with dyspnea and eye pain. A chest radiograph done at that time demonstrated hilar adenopathy and pulmonary parenchymal infiltrates. Transbronchial biopsies were performed, and specimens showed epithelioid granulomas, leading to a diagnosis of sarcoidosis. Her dyspnea improved with prednisone, but she was subsequently lost to follow-up. On current presentation, she has no complaints of cough, ocular pain, visual changes, skin lesions, or other systemic symptoms. Her medical history includes schizophrenia, depression, and osteopenia. Medications were lamictal, fluoxamine, seroquel, and depakote. The patient is a nonsmoker and lifelong resident of New York state. She has no history of travel or sick contacts. Family history is notable for laryngeal cancer in her father.

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