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Editorials: POINT/COUNTERPOINT EDITORIALS |

Counterpoint: Adherence to Early Goal-Directed Therapy: Does It Really Matter? No. Both Risks and Benefits Require Further Study

Gregory A. Schmidt, MD, FCCP
Author and Funding Information

From the Division of Pulmonary Diseases, Critical Care, and Occupational Medicine, Department of Internal Medicine, University of Iowa.

Correspondence to: Gregory A. Schmidt, MD, FCCP, Division of Pulmonary Diseases, Critical Care, and Occupational Medicine, Department of Internal Medicine, University of Iowa, 200 Hawkins Dr, C304-GH, Iowa City, IA 52242; e-mail: Gregory-a-schmidt@uiowa.edu


Financial/nonfinancial disclosures: The author has reported to CHEST that no potential conflicts of interest exist with any companies/organizations whose products or services may be discussed in this article.

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (http://www.chestpubs.org/site/misc/reprints.xhtml).


© 2010 American College of Chest Physicians


Chest. 2010;138(3):480-483. doi:10.1378/chest.10-1400
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In a landmark article published in 2001, patients with severe sepsis presenting to an ED were more likely to survive when treated with a multifaceted protocol called early goal-directed therapy (EGDT).1 By 2004, the Surviving Sepsis Campaign (SSC) advocated this approach,2 and soon after, the Institute for Healthcare Improvement, several professional societies, and others urged the adoption of sepsis bundles, including elements derived from EGDT, both to improve patient safety and as a quality measure.

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